Osamu Taguchi Selected Research

Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)

10/2013	Thrombin-activatable fibrinolysis inhibitor protects against acute lung injury by inhibiting the complement system.
4/2012	Role of thrombin-activatable fibrinolysis inhibitor in allergic bronchial asthma.
4/2009	Presence of thrombin-activatable fibrinolysis inhibitor in Helicobacter pylori-associated gastroduodenal disease.
7/2008	Immune complex-mediated glomerulonephritis is ameliorated by thrombin-activatable fibrinolysis inhibitor deficiency.
4/2006	Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis.
7/2004	Increased circulating levels of thrombin-activatable fibrinolysis inhibitor in lung cancer patients.
6/2003	Thrombin-activatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease.

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Osamu Taguchi Research Topics

Disease

18	Neoplasms (Cancer) 11/2018 - 04/2002
11	Fibrosis (Cirrhosis) 01/2022 - 03/2002
11	Inflammation (Inflammations) 01/2019 - 05/2003
11	Asthma (Bronchial Asthma) 01/2019 - 03/2004
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 06/2012
7	Lung Neoplasms (Lung Cancer) 01/2022 - 10/2003
5	Pneumonia (Pneumonitis) 02/2011 - 05/2003
4	Respiratory Hypersensitivity 01/2019 - 05/2004
4	Insulin Resistance 10/2018 - 08/2006
3	Chronic Obstructive Pulmonary Disease (COPD) 01/2018 - 01/2013
3	Neoplasm Metastasis (Metastasis) 03/2012 - 12/2010
3	Osteosarcoma (Osteogenic Sarcoma) 03/2012 - 12/2010
3	Lung Injury 12/2007 - 05/2004
2	Adenocarcinoma of Lung 02/2018 - 03/2014
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2017 - 03/2012
2	Idiopathic Pulmonary Fibrosis 10/2017 - 03/2002
2	Hypersensitivity (Allergy) 01/2015 - 12/2014
2	Acute Lung Injury 10/2013 - 10/2004
2	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 04/2013 - 09/2008
2	Interstitial Lung Diseases (Interstitial Lung Disease) 05/2012 - 06/2003
2	Leukemia 04/2011 - 11/2004
2	Thrombophilia 08/2009 - 02/2003
2	Infections 08/2008 - 08/2005
2	Lymphoma (Lymphomas) 11/2004 - 04/2002
1	Glaucoma 01/2022
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2022
1	Wounds and Injuries (Trauma) 01/2022
1	Lambert-Eaton Myasthenic Syndrome (Lambert-Eaton Syndrome) 01/2022
1	Cicatrix (Scar) 01/2022
1	Hemoptysis 01/2020
1	Varicose Veins (Varicose Vein) 01/2020
1	Radiation Pneumonitis 09/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Erythema 01/2019

Drug/Important Bio-Agent (IBA)

9	OvalbuminIBA 01/2015 - 11/2003
8	CytokinesIBA 01/2019 - 03/2004
8	AntigensIBA 04/2007 - 06/2003
7	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 10/2013 - 06/2003
6	CollagenIBA 01/2022 - 05/2004
6	Monoclonal AntibodiesIBA 01/2019 - 01/2006
6	Bleomycin (Blenoxane)FDA LinkGeneric 10/2017 - 03/2002
5	ThrombomodulinIBA 10/2017 - 08/2009
5	Protein CIBA 01/2015 - 05/2003
4	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2019 - 10/2011
4	Immunoglobulin E (IgE)IBA 01/2019 - 03/2004
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2017 - 12/2007
4	VaccinesIBA 03/2010 - 10/2003
4	Proteins (Proteins, Gene)FDA Link 12/2007 - 02/2004
4	Neoplasm Antigens (Tumor Antigens)IBA 04/2007 - 10/2003
4	DNA (Deoxyribonucleic Acid)IBA 03/2007 - 04/2002
3	ErbB Receptors (EGF Receptor)IBA 01/2021 - 08/2018
3	AntibodiesIBA 01/2019 - 11/2002
3	LipidsIBA 01/2019 - 01/2017
3	AllergensIBA 01/2019 - 12/2006
3	Tyrosine Kinase InhibitorsIBA 01/2019 - 02/2018
3	AnticoagulantsIBA 10/2017 - 05/2003
3	Peptides (Polypeptides)IBA 07/2014 - 11/2003
3	Small Interfering RNA (siRNA)IBA 01/2013 - 04/2011
3	Interleukin-5 (Interleukin 5)IBA 04/2012 - 01/2006
3	Thrombin FDA Link 11/2008 - 08/2005
2	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2019 - 01/2018
2	AfatinibIBA 01/2019 - 08/2018
2	Blood Glucose (Blood Sugar)IBA 01/2019 - 05/2016
2	Insulin (Novolin)FDA Link 10/2018 - 05/2016
2	Glucose (Dextrose)FDA LinkGeneric 10/2018 - 01/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2018 - 01/2006
2	CrizotinibIBA 09/2018 - 01/2017
2	osimertinibIBA 08/2018 - 02/2018
2	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 01/2004
2	Interferon-gamma (Interferon, gamma)IBA 01/2017 - 03/2007
2	Messenger RNA (mRNA)IBA 07/2014 - 10/2004
2	Complement System Proteins (Complement)IBA 10/2013 - 04/2012
2	Interleukin-2 (IL2)IBA 03/2012 - 01/2006
2	Transcription Factors (Transcription Factor)IBA 04/2011 - 12/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2011 - 05/2006
2	Glycoproteins (Glycoprotein)IBA 01/2010 - 12/2006
2	antithrombin III-protease complexIBA 08/2009 - 02/2003
2	Fibrinogen (Factor I)FDA Link 07/2008 - 04/2006
2	Therapeutic UsesIBA 12/2007 - 05/2004
2	AutoantigensIBA 01/2006 - 11/2004
2	indium-bleomycinIBA 10/2004 - 05/2004
2	Platelet-Derived Growth FactorIBA 05/2004 - 05/2003
2	DNA VaccinesIBA 11/2003 - 04/2002
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	durvalumabIBA 09/2019
1	Imiquimod (Aldara)FDA LinkGeneric 01/2019
1	Interleukin-17 (Interleukin 17)IBA 01/2019
1	Cetuximab (Erbitux)FDA Link 01/2019

Therapy/Procedure

16	Therapeutics 09/2019 - 05/2006
6	Radiofrequency Ablation 03/2014 - 05/2004
5	Immunotherapy 04/2007 - 04/2002
2	Transplantation 12/2014 - 03/2012
2	Electrodes (Electrode) 03/2014 - 05/2004
2	Aftercare (After-Treatment) 01/2013 - 03/2007
2	Home Nursing (Nursing, Home) 04/2010 - 03/2010
1	Surgical Instruments (Clip) 01/2022
1	Filtering Surgery 01/2022
1	Sclerotherapy 01/2020
1	Chemoradiotherapy 09/2019